INTEGRATING MACHINE LEARNING MODELS WITH MULTI-OMICS ANALYSIS TO DECIPHER THE PROGNOSTIC SIGNIFICANCE OF MITOTIC CATASTROPHE HETEROGENEITY IN BLADDER CANCER

Abstract Background Mitotic catastrophe is well-known as a major pathway of endogenous tumor death, but the prognostic significance of its heterogeneity regarding bladder cancer (BLCA) remains unclear.Methods Our study focused on digging deeper into the TCGA and GEO databases.Through differential expression analysis as well as Weighted Gene Co-expr

The objective of the present study was to investigate selected trace and mineral elements in Royal Jelly (RJ) from Bulgaria.A total of 30 RJ samples were included in the study.The analytical procedure consisted of the microwave digestion of the RJ samples with nitric acid followed by instrumental measurement.Concentrations of Al, Ba, Ca, Cr, Cu, Fe

Path-specific effect analysis is a powerful tool in causal inference.This paper provides a definition of causal counterfactual path-specific importance score for the structural causal model (SCM).Different from existing path-specific effect definitions, which focus Bud Vase on the population level, the score defined in this paper can quantify the i

We present the case of a 25-year-old male patient with a history of gunshot wound in the chest 3 years before, who developed symptoms in the arm for 1 year.The patient was assessed by the outpatient clinic, presenting left subclavian murmur, and development of venous network.Three-dimensional Massagers rotational angiography revealed left subclavia

Dalam penelitian ini ada dua hal yang peneliti kemukakan didalam rumusan masalah yaitu pertama, bagaimana keberadaan sanksi pidana kebiri kimia sebagai pidana tambahan terhadap pelaku kekerasan seksual pada anak ditinjau dari perspektif tujuan pemidanaan dalam kebijakan hukum nasional.Kedua, bagaimana kedudukan sanksi pidana kebiri kimia dalam kebi